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1

Antibiotics GE23077, Novel Inhibitors of Bacterial RNA Polymerase. Part 1. Taxonomy, Isolation and Characterization.

Ismaela Ciciliato, Emiliana Corti, Edoardo Sarubbi, Stefania Stefanelli, Luciano Gastaldo, Nicoletta Montanini, Michael Kurz, Daniele Losi, Flavia Marinelli, Enrico Selva

Journal:

Année:

2004

Fichier:

PDF, 71 KB

2004

2

Src homology-2 domain binding assays by scintillation proximity and surface plasmon resonance

Eliane Mandine, Dominique Gofflo, Véronique Jean-Baptiste, Edoardo Sarubbi, Gaetan Touyer, Pierre Deprez, Dominique Lesuisse

Journal:

Journal of Molecular Recognition

Année:

2001

Langue:

english

Fichier:

PDF, 124 KB

english, 2001

3

A Cell-Free, Nonisotopic, High-Throughput Assay for Inhibitors of Type-I Interleukin-1 Receptor

Edoardo Sarubbi, Stephen D. Yanofsky, Ronald W. Barrett, Maurizio Denaro

Journal:

Analytical Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 118 KB

english, 1996

4

Protein batches from downstream processing studies can be cost-effective tools for fast and specific protein quantification assays

Edoardo Sarubbi

Journal:

Analytical Biochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 115 KB

english, 2005

5

Discovery of Thioazepinone Ligands for Src SH2: From Non-specific to Specific Binding

Dominique Lesuisse, Pierre Deprez, Eva Albert, Tran Thien Duc, Benoit Sortais, Dominique Gofflo, Véronique Jean-Baptiste, Jean-Pierre Marquette, Bernard Schoot, Edoardo Sarubbi, Gudrun Lange, Pierre B

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 465 KB

english, 2001

6

Basal ppGpp level adjustment shown by newspoTmutants affect steady state growth rates andrrnAribosomal promoter regulation inEscherichia coli

Edoardo Sarubbi, Kenneth E. Rudd, Michael Cashel

Journal:

Molecular Genetics and Genomics

Année:

1988

Langue:

english

Fichier:

PDF, 1014 KB

english, 1988

7

Charge heterogeneity of recombinant pro-urokinase and urinary urokinase, as revealed by isoelectric focusing in immobilized pH gradients

Pier Giorgio Righetti, Barbara Barzaghi, Edoardo Sarubbi, Adolfo Soffientini, Giovanni Cassani

Journal:

Journal of Chromatography A

Année:

1989

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1989

8

Mode of action of the microbial metabolite GE23077, a novel potent and selective inhibitor of bacterial RNA polymerase

Edoardo Sarubbi, Federica Monti, Emiliana Corti, Anna Miele, Enrico Selva

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 383 KB

english, 2004

9

A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

Schreuder, Herman, Tardif, Chantal, Trump-Kallmeyer, Susanne, Soffientini, Adolfo, Sarubbi, Edoardo, Akeson, Ann, Bowlin, Terry, Yanofsky, Stephen, Barrett, Ronald W.

Journal:

Année:

1997

Fichier:

PDF, 2.17 MB

1997

10

An elongation factor Tu (EF-Tu) resistant to the EF-Tu inhibitor GE2270 in the producing organism Planobispora rosea

Margherita Sosio, Giuseppe Amati, Carmela Cappellano, Edoardo Sarubbi, Federica Monti, Stefano Donadio

Journal:

Molecular Microbiology

Année:

1996

Langue:

english

Fichier:

PDF, 994 KB

english, 1996

11

Particle concentration fluorescence as an alternative to radioactivity for cytokine receptor binding assays

Edoardo Sarubbi

Journal:

Journal of Immunological Methods

Année:

1996

Langue:

english

Fichier:

PDF, 524 KB

english, 1996

12

Refined Crystal Structure of the Interleukin-1 Receptor Antagonist : Presence of a Disulfide Link and a cis -Proline

Herman A. Schreuder, Jean Michel Rondeau, Chantal Tardif, Adolfo Soffientini, Edoardo Sarubbi, Ann Akeson, Terry L. Bowlin, Stephen Yanofsky, Ronald W. Barrett

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 3.16 MB

english, 1995

13

Endogenous Glutathione-Binding Proteins of Insect Cell Lines: Characterization and Removal from Glutathione S-Transferase (GST) Fusion Proteins

Paulette Bichet, Patrick Mollat, Cécile Capdevila, Edoardo Sarubbi

Journal:

Protein Expression and Purification

Année:

2000

Langue:

english

Fichier:

PDF, 95 KB

english, 2000

14

A high throughput assay for inhibitors of HIV-1 protease Screening of microbial metabolites

Edoardo Sarubbi, M.Luisa Nolli, Franca Andronico, Sergio Stella, Gerard Saddler, Enrico Selva, Antonio Siccardi, Maurizio Denaro

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 422 KB

english, 1991

15

Epitope mapping of a monoclonal antibody which binds HIV-1 Gag and not the Gag-derived proteins

Edoardo Sarubbi, Maurizio Denaro

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 434 KB

english, 1993

16

Peptide aldehydes as inhibitors of HIV protease

Edoardo Sarubbi, Pier Fausto Seneci, Michael R. Angelastro, Norton P. Peet, Maurizio Denaro, Khalid Islam

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 378 KB

english, 1993

17

Crystals of soluble interleukin-1 receptor complexed with its natural antagonist reveal a 1:1 receptor-ligand complex

Herman Schreuder, Chantal Tardif, Adolfo Soffientini, Edoardo Sarubbi, Ann Akeson, Terry Bowlin, Stephen Yanofsky, Ronald W. Barrett

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 215 KB

english, 1995

18

High-affinity Src-SH2 ligands which do not activate Tyr527-phosphorylated Src in an experimental in vivo system

Eliane Mandine, Véronique Jean-Baptiste, Béatrice Vayssière, Dominique Gofflo, Didier Bénard, Edoardo Sarubbi, Pierre Deprez, Roland Baron, Giulio Superti-Furga, Dominique Lesuisse

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 192 KB

english, 2002

19

Effect of blood gas derangement on QTc dispersion in severe chronic obstructive pulmonary disease: evidence of an electropathy?

Berardo Sarubbi, Vincenzo Esposito, Valentino Ducceschi, Ilernando Meoli, Edoardo Grella, Lucio Santangelo, Aldo Iacano, Mario Caputi

Journal:

International Journal of Cardiology

Année:

1997

Langue:

english

Fichier:

PDF, 153 KB

english, 1997

20

Requirements for Specific Binding of Low Affinity Inhibitor Fragments to the SH2 Domain of pp60 Src Are Identical to Those for High Affinity Binding of Full Length Inhibitors

Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 821 KB

english, 2003

21

Evaluation of phenylboronate agarose for industrial-scale purification of erythropoietin from mammalian cell cultures

Dino Zanette, Adolfo Soffientini, Cristina Sottani, Edoardo Sarubbi

Journal:

Journal of Biotechnology

Année:

2003

Langue:

english

Fichier:

PDF, 430 KB

english, 2003

22

Human IL-1 receptor antagonist from Escherichia coli: Large-scale microbial growth and protein purification

Dino Zanette, William Dundon, Adolfo Soffientini, Cristina Sottani, Flavia Marinelli, Ann Akeson, Edoardo Sarubbi

Journal:

Journal of Biotechnology

Année:

1998

Langue:

english

Fichier:

PDF, 187 KB

english, 1998

23

Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes

Klabunde, Thomas, Wendt, K. Ulrich, Kadereit, Dieter, Brachvogel, Volker, Burger, Hans-Jörg, Herling, Andreas W., Oikonomakos, Nikos G., Kosmopoulou, Magda N., Schmoll, Dieter, Sarubbi, Edoardo, von R

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 667 KB

english, 2005

24

Principles Governing the Binding of a Class of Non-Peptidic Inhibitors to the SH2 Domain of src Studied by X-ray Analysis

Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane

Journal:

Journal of Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 629 KB

english, 2002

25

Antibiotics GE23077, Novel Inhibitors of Bacterial RNA Polymerase I. Taxonomy, Isolation and Characterization

CICILIATO, ISMAELA, CORTI, EMILIANA, SARUBBI, EDOARDO, STEFANELLI, STEFANIA, GASTALDO, LUCIANO, MONTANINI, NICOLETTA, KURZ, MICHAEL, LOSI, DANIELE, MARINELLI, FLAVIA, SELVA, ENRICO

Journal:

The Journal of Antibiotics

Année:

2004

Langue:

english

Fichier:

PDF, 906 KB

english, 2004